And thats the point it doesnt work.... with blue pill or high Lust, it doesn´t work. BTW I´ve read all things in this game.
Check your questlog on your phone if you have X/3 where X is 2 or lower, you need to fap more with taking a bluepill, else you are on track for the High quality sperm quest. As you can only deliver this quest in if you have 3 or more vials ready for her. Also and probably you already know you get a new blue pill each time you deliver 3 normal sperm samples. ( in my games they can start a spermbank already, unless they use it for other goals like protein shakes in the restaurant, superfoods ftw?)
So recap:
1. check quest log to see how many high ones you need
2 get a blue pill from doc and have some empty vials and take blue pill, through the phone app, inventory
3. get high lust, check the icons top left for selfbuffs/debuffs on you (tuired, hungry, high lust) to see if you have that lust and have taken blue pill
4. masturbate
5. check quest log again to see if it progressed.
Done.
If at step 5 you have not progressed i would if i were you post: a. a screenshot, b. your game version you're using and c. a savefille for the developer to see what the bug is. Cause after that point i do not think any of us players can help you anymore